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apalutamide will lessen the extent or impact of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a robust CYP2C19 inducer, with prescription drugs which have been CYP2C19 substrates can lead to reduced publicity to those remedies.Reserve concomitant prescribing of those medicatio